The research program at the RAH Colorectal Research Group has three main stems which cover major areas in colorectal patient care: Post-operative recovery, colorectal surgical oncology, and inflammatory bowel disease.
Current and recent research activity is summarised below:
LaNoReC (Lateral Nodal Recurrence in Rectal Cancer): An international prospective registration study looking at the role of ateral pelvic lymph node dissection for residual abnormal lateral nodes in patients with rectal cancer. dccg.nl/trial/lanorec
DAMASCUS (Diverticular Abscess Management: A Snapshot Collaborative aUdit Study) is an international, prospective study aiming to investigate the variations in the management of patients with diverticular abscess and whether these variations are associated with short term clinical outcomes at 30 days or with readmission or re-intervention rates over the subsequent 6 months.
Protocol here: www.acpgbi.org.uk/news/damascus-study-in-the-uk/
PyRICo-RCT: Pyridostigmine to reduce the duration of postoperative ileus after colorectal surgery - a double-blinded randomised controlled trial (ethics submission phase): www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=381752
mASCARA: Multinational Anal Squamous Cell Carcinoma: Registry and Audit. Longitudinal registry study looking to collect international data on anal SCC or high-grade AIN patients (data collection phase): mascararegistry.com/about/
Artificial intelligence and deep learning to more accurately diagnose positive lymph node disease on pre-operative imaging in colorectal cancer and assess the impact of sarcopenia on colorectal cancer outcomes (data collection phase).
TNT prospective study of Total Neoadjuvant Therapy in locally advanced and stage IV rectal cancer (data collection phase).
RENO: Prospective Study of ‘Watch and Wait’ Strategy in Patients with Rectal Cancer who have Developed a Clinical Complete Response with concurrent Chemo‐radiotherapy: RENO trial (REctal cancer No Operation).
Protocol here: https://gicancer.org.au/clinical-trial/reno/#health-professionals
Current and recent research activity is summarised below:
LaNoReC (Lateral Nodal Recurrence in Rectal Cancer): An international prospective registration study looking at the role of ateral pelvic lymph node dissection for residual abnormal lateral nodes in patients with rectal cancer. dccg.nl/trial/lanorec
DAMASCUS (Diverticular Abscess Management: A Snapshot Collaborative aUdit Study) is an international, prospective study aiming to investigate the variations in the management of patients with diverticular abscess and whether these variations are associated with short term clinical outcomes at 30 days or with readmission or re-intervention rates over the subsequent 6 months.
Protocol here: www.acpgbi.org.uk/news/damascus-study-in-the-uk/
PyRICo-RCT: Pyridostigmine to reduce the duration of postoperative ileus after colorectal surgery - a double-blinded randomised controlled trial (ethics submission phase): www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=381752
mASCARA: Multinational Anal Squamous Cell Carcinoma: Registry and Audit. Longitudinal registry study looking to collect international data on anal SCC or high-grade AIN patients (data collection phase): mascararegistry.com/about/
Artificial intelligence and deep learning to more accurately diagnose positive lymph node disease on pre-operative imaging in colorectal cancer and assess the impact of sarcopenia on colorectal cancer outcomes (data collection phase).
TNT prospective study of Total Neoadjuvant Therapy in locally advanced and stage IV rectal cancer (data collection phase).
RENO: Prospective Study of ‘Watch and Wait’ Strategy in Patients with Rectal Cancer who have Developed a Clinical Complete Response with concurrent Chemo‐radiotherapy: RENO trial (REctal cancer No Operation).
Protocol here: https://gicancer.org.au/clinical-trial/reno/#health-professionals